First, make sure tracks are playing on both CDJs. If you still don't hear anything, work through these in order:
1. Check the speakers are powered on — look for the LED light on the front of each one. There's a power switch on the back of the speaker itself, and another at the wall socket.
2. Check the channel dials on the DJM. Each channel has a mode selector at the top — set it to LINE if you're using a USB stick, or A/B (matching whichever port your laptop's third USB cable is plugged into) if using a laptop. Leeds location only: set all dials to DIGITAL instead.
3. Set the BALANCE and MASTER VOL knobs to the middle position. See this quick guide for more.